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VITA PRESS
Supports Blood Pressure Levels Already in the Normal
Range

DESCRIPTION
VITA PRESS, provided by Vitasecrets, is a novel
blend of natural ingredients, including unique
milk-derived tripeptides, grape seed extract, herbs,
vitamins, minerals and amino acids designed to
support the body’s natural blood pressure regulatory
mechanism and maintain proper cardiovascular
function.
FUNCTIONS
The ingredients in VITA PRESS are designed to work
synergistically to support already healthy blood
pressure, vascular and circulatory function, and
general cardiovascular health.
AmealPeptide®
AmealPeptide is a combination of two bioactive
tripeptides (Valyl-Prolyl-Proline and
Isoleucyl-Prolyl-Proline) that support the body’s
regulatory blood pressure mechanism. AmealPeptide is
derived from a proprietary process involving the
enzymatic hydrolysis of casein (milk protein). The
hydrolyzed milk protein contains bioactive
tri-peptides that are thought to play important
roles by limiting the conversion of angiotensin I to
angiotensin II caused by the body’s production of
angiotensin converting enzyme (ACE), a key enzyme
that regulates blood pressure. Angiotensin II is a
vasopressor and can influence the kidney’s retention
of water and salt. By maintaining a healthy
conversion of angiotensin I to angiotensin II with
use of AmealPeptide, healthy blood pressure can be
regulated and maintained. Fourteen short term and
long term human studies show that AmealPeptide can
support this natural regulation of healthy blood
pressure.
MegaNatural®
BP Grape Seed Extract
Grape seed extract is well regarded for the
beneficial role it can play in cardiovascular and
antioxidant health. MegaNatural BP Grape seed
extract is different from other grape seed extracts
and made by a novel, patented water extraction
process that yields a high grade extract with a low
molecular weight. Mega Natural BP extract contains
over 90% proanthocyanidins. Proanthocyanidins are
highly regarded for their strong antioxidant
properties, and for their functions in supporting
the body’s connective tissues and capillary blood
vessel system. Mega Natural BP grape seed extract
has shown in studies to be superior to other grape
seed extracts in its ability to prevent LDL (low
density lipid) cholesterol oxidation. Studies in
humans also show it can support already healthy
blood pressure levels, as well as maintaining normal
arterial function and endothelium cell function. In
one human study, patients with metabolic syndrome
were given Mega Natural BP grape seed extract or
placebo. This extract was found to support the
patients’ blood pressure levels already within
normal ranges, whereas the placebo showed no
significant change.
Hawthorn Extract
The cardiotherapeutic properties of hawthorn are due
to its high content of many biologically active
flavonoid compounds, including anthocyanidins,
proanthocyanidins, quercetin, vitexin, vitexin
ramnoside, as well as catechin and epicatechin.
Hawthorn extract has been shown in human as well as
animal studies to improve circulation by dilating
coronary blood vessels. Dilation of these blood
vessels consequently increases blood, and thus
oxygen supply to the heart. Components of hawthorn
extract have also been demonstrated to regulate the
effects of angiotensin-converting enzyme, thus
supporting healthy blood vessel constriction.
Arginine
As a precursor of nitric oxide, L-arginine serves to
help support the healthy function of blood vessels
and vascular tissue. L-arginine is also required for
the synthesis of creatine phosphate. Similar to
adenosine triphosphate (ATP), creatine phosphate
functions as a carrier of readily available energy
for contractile work in muscles. Adequate reservoirs
of creatine phosphate are necessary in muscle as an
energy reserve for anaerobic activity.
Nattokinase
Nattokinase is a serine endopeptidase consisting of
275 amino acids. Laboratory studies indicate that
nattokinase possesses stronger fibrinolytic activity
than other known enzymes. Fibrinolysis is a normal
biological process and an important part of an
organism’s ability to heal wounds and regulate blood
clotting. Proper regulation of fibrinolysis can help
maintain a healthy flow of blood through the
vascular system and ensure that the body’s major
organs are continually supplied by oxygen, nutrients
and other necessary products for complete health.†
(continued on next page)
Coleus
In its native India, coleus has been used in the
ancient medical system of Ayurveda for centuries.
Laboratory and clinical studies have documented
several benefits of forskolin. Forskolin has cardiac
inotropic properties in that it appears to help
strengthen heart muscle contractability. Forskolin
promotes vasodilation, thereby helping to support
healthy peripheral vascular
resistance. Compounds in coleus including, but not
limited to, forskolin, provide further benefit to
the cardiovascular system by supporting healthy
platelet function. Forskolin has also been shown to
promote bronchodilation, in part by helping to relax
airway smooth muscles and by maintaining healthy
histamine and leukotriene release.
Vitamins, Minerals and Cardiovascular Function
Homocysteinemia, or elevated plasma homocysteine, is
quickly emerging as a major, independent risk factor
of cardiovascular diseases. High plasma levels of
homocysteine appear to injure the vasculature,
impairing the functional abilities of endothelial
and smooth muscle cells. Suboptimal intake of
several B vitamins, renal failure, and genetic
defects in homocysteine metabolism can all
contribute to abnormal homocysteine levels.
Production of cysteine from homocysteine requires
two specific enzymes for which vitamin B6
is an essential coenzyme. Without
adequate vitamin B6
available, homocysteine can not be
metabolized into cysteine.
The body can also rid itself of homocysteine by
remethylating it to methionine. The primary route by
which homocysteine is remethylated to methionine
requires methyltetrahydrofolate as a methyl donor
and vitamin B12
as a coenzyme. Methyltetrahy-drofolate
is created in the body from dietary folic acid.
Vitamin C (ascorbic acid) has numerous biological
functions. Foremost, it is essential for the
synthesis of collagen and glycosaminoglycans which
are the building materials of all connective
tissues, such as skin, blood vessels, tendons, joint
cartilage and bone. Vitamin C is the required
coenzyme for two groups of enzymes that catalyze the crosslinking of collagen fibers-lysyl hydroxylases
and prolyl hydroxylases. As such, vitamin C is
essential for normal wound healing and capillary
health.
Vitamin C is among the most powerful antioxidants in
humans and animals. It is a water-soluble,
chain-breaking antioxidant that reacts directly with
superoxide, hydroxyl radicals, and singlet oxygen.
Laboratory studies show that vitamin C completely
protects lipids in plasma and low-density
lipoprotein (LDL) against atherogenic peroxidative
damage. In addition, vitamin C interacts with
glutathione and alpha-lipoic acid, and regenerates
vitamin E.
Magnesium plays an essential role in a wide range of
fundamental cellular reactions. More than 300
enzymes require magnesium as a cofactor. Complexed
with ATP, the main carrier of metabolic energy in
the body, magnesium is essential for all
biosynthetic processes, glycolysis, formation of
c-AMP, energy-dependent membrane transport,
trans-mission of genetic code for protein synthesis,
and muscle function.
INDICATIONS
VITA PRESS may be a useful dietary supplement for
individuals wishing to support cardiovascular
function and support blood pressure already in the
normal range.
FORMULA
4
vegetarian capsules contain:
AmealPeptide®
Hydrolyzed Casein Extract
(milk).............. 710 mg (providing 5 mg of
Valyl-Prolyl-Proline and Isoleucyl-Prolyl-Proline)
Vitamin C
..................................................
250 mg
(as magnesium and potassium ascorbates)
Vitamin B-6
................................................. 10
mg
Vitamin B-12 (as methylcobalamin) .......... 500 mcg
Folic acid
...................................................
800 mcg
Calcium (as calcium citrate)
........................ 50 mg
Magnesium (as taurinate/ascorbate) .......... 100 mg
L-Arginine HCl
......................................... 150 mg
Hawthorn extract (leaf and flower) ............ 250
mg
(standardized to 1.8% vitexin-2- rhamnoside and
hyperoside)
Coleus extract (root)
.................................. 125 mg
(standardized to 10% forskolin)
Olive leaf extract
....................................... 150 mg
(standardized to 15% oleuropein)
Nattokinase (NSK-SD™) .......................... 500
FU
Mega Natural®
BP grape seed extract ........ 150 mg
Mega Natural®
BP is a trademark of Polyphenolics, a
division of Constellation Wines U.S., Inc.
AmealPeptide®
is a registered trademark of Calpis
Co., Ltd.
NSK-SD™
is a registered trademark of Japan
BioScience Laboratories
SUGGESTED USE
Adults take 4 or more capsules with meals or as
directed by physician.
SIDE EFFECTS
Do no use if you are pregnant or breast feeding, if
you are taking anticoagulant drugs (such as Warfarin)
or other medications that effect blood clotting, or
if you are at risk for any bleeding disorder.
STORAGE
Store in a cool, dry place, away from direct light.
Keep out of reach of children.
These statements have not been evaluated by the Food
and Drug Administration.
This product is not intended to diagnose, treat,
cure, or prevent any disease.
REFERENCES
Aronow WS, Ahn C. Association between plasma
homocystein and peripheral arterial disease in older
persons. Coron Artery Dis 1998;9:49-50.
Ballmer PE, Reinhart WH, Jordan P, Bühler E, Moser
UK, Gey KF. Depletion of plasma vitamin C but not of
vitamin E in response to cardiac operations. J Thorac Cardiovasc Surg 1994;108:311-320.
Bhat SV et al. The antihypertensive and positive
inotropic diterpene
forskolin: effects of structural modifications on
its activity. Journal of Med Chem 1983;26:486-492.
Blazso G and Gabor M: Oedema-inhibiting effect of
procyanidin. Acta Physiologica Scientariium
Hungaricae, Tomus 1980;56 (2):235-40.
Robert L et al: Action of procyanidolic oligomers on
vascular permeability. Path Biol 1990;38:608-616.
Blesken R. [Crataegus in cardiology]. Fortschr Med
1992;110:290-2.
Sekiya S et al, Antihypertensive effects of tryptic
hydrolysate of casein on normotensive and
hypertensive volunteers. J. Jpn. Soc. Nutr. Food
Sci. 1992; 45:513-517.

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